Yoav Ram's blog

Posted Sun 16 June 2013

Summary: “Balancing robustness and evolvability” (Lenski et al. 2006)

This is a summary of Lenski, Barrick and Ofria (2006). The following are direct quotes of the original article. My comments are given as footnotes, highlighting and italics.


The original paper was published in PLoS Biology under a CC-BY license.


Lenski, Richard E., Jeffrey E. Barrick, and Charles Ofria. 2006. “Balancing robustness and evolvability.” PLoS Biology 4 (12): e428. doi:10.1371/journal.pbio.0040428.

Meyers, Lauren Ancel, Fredric D Ancel, and Michael Lachmann. 2005. “Evolution of genetic potential.” Edited by Eddie Holmes. PLoS Computational Biology 1 (3). Public Library of Science: 236–43. doi:10.1371/journal.pcbi.0010032.

  1. Low mutation rate (U)

  2. Small mutation effect (s)

  3. The amplification model

Category: evolution